Nicorandil induced penile ulceration
نویسندگان
چکیده
We report the unusual complication of penile ulceration caused by Nicorandil, a nicotinamide ester used in the treatment of symptomatic angina pectoris.
منابع مشابه
Nicorandil-induced penile ulceration: a case report
BACKGROUND Penile ulceration in older patients is commonly neoplastic or infective. However, there are rarer causes of these ulcerations that we have to exclude. We present a rare complication of penile ulceration secondary to nicorandil, a nicotinamide ester. CASE PRESENTATION An 86-year-old white British man was referred with a bloody discharge from under his phimotic foreskin and a lump on...
متن کاملPenile Ulceration Secondary to Nicorandil Use
Nicorandil is a medication used for treatment and prevention of angina pectoris. Its mode of action involves both arterial and venous vasodilation. Although there are numerous known side effects, one of the more unusual, adverse reactions is ulceration of the external genitalia. This case reports the finding of penile preputial ulceration secondary to the use of Nicorandil. The authors make som...
متن کاملLetter: Nicorandil-Induced Peristomal Ulceration
Dear Sirs Nicorandil (Ikorel; Rhône–Poulenc Rorer, Guildford, UK) is a potassium-channel activator used in the treatment of severe ischaemic heart disease. It causes anal and oral ulceration. We report the case of the rare phenomenon of Nicorandil-induced peristomal ulceration, the severity of which almost required plastic surgery input. A 71-year-old lady, who had a Hartmann’s procedure 5 year...
متن کاملA case of nicorandil-induced unilateral corneal ulceration.
Nicorandil, a second-generation nitro derivative, has been reported to induce single or multiple ulcerations in many locations, including oral, anal, perianal, vulvovaginal, perivulval, penile, gastrointestinal, colic, peristomal and skin locations. Ocular locations are now highly suspected. Herein, we report the case of a 78-year-old woman who experienced corneal ulceration at second cataract ...
متن کاملPersistent nicorandil induced oral ulceration.
Four patients with nicorandil induced ulceration are described, and the literature on the subject is reviewed. Nicorandil induced ulcers are very painful and distressing for patients. Clinically they appear as large, deep, persistent ulcers that have punched out edges. They are poorly responsive to topical steroids and usually require alteration of nicorandil treatment. The ulceration tends to ...
متن کامل